Investigation of Enantioselective Membrane Permeability of α-Lipoic Acid in Caco-2 and MDCKII Cell

α-Lipoic acid (LA) contains a chiral carbon and exists as two enantiomers (R-α-lipoic acid (RLA) and S-α-lipoic acid (SLA)). We previously demonstrated that oral bioavailability of RLA is better than that of SLA. This difference arose from the fraction absorbed multiplied by gastrointestinal availab...

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Detalles Bibliográficos
Autores principales: Uchida, Ryota, Okamoto, Hinako, Ikuta, Naoko, Terao, Keiji, Hirota, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783889/
https://www.ncbi.nlm.nih.gov/pubmed/26821014
http://dx.doi.org/10.3390/ijms17020155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783889/
https://www.ncbi.nlm.nih.gov/pubmed/26821014
http://dx.doi.org/10.3390/ijms17020155

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