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A Common Variant of PROK1 (V67I) Acts as a Genetic Modifier in Early Human Pregnancy through Down-Regulation of Gene Expression

PROK1-V67I has been shown to play a role as a modifier gene in the PROK1-PROKR system of human early pregnancy. To explore the related modifier mechanism of PROK1-V67I, we carried out a comparison study at the gene expression level and the cell function alternation of V67I, and its wild-type (WT), i...

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Detalles Bibliográficos
Autores principales: Su, Mei-Tsz, Huang, Jyun-Yuan, Tsai, Hui-Ling, Chen, Yi-Chi, Kuo, Pao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783896/
https://www.ncbi.nlm.nih.gov/pubmed/26828479
http://dx.doi.org/10.3390/ijms17020162