Cargando…

A Common Variant of PROK1 (V67I) Acts as a Genetic Modifier in Early Human Pregnancy through Down-Regulation of Gene Expression

PROK1-V67I has been shown to play a role as a modifier gene in the PROK1-PROKR system of human early pregnancy. To explore the related modifier mechanism of PROK1-V67I, we carried out a comparison study at the gene expression level and the cell function alternation of V67I, and its wild-type (WT), i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Mei-Tsz, Huang, Jyun-Yuan, Tsai, Hui-Ling, Chen, Yi-Chi, Kuo, Pao-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783896/ https://www.ncbi.nlm.nih.gov/pubmed/26828479 http://dx.doi.org/10.3390/ijms17020162

Ejemplares similares

The prognosis was poorer in colorectal cancers that expressed both VEGF and PROK1(No correlation coefficient between VEGF and PROK1)
por: Goi, Takanori, et al.
Publicado: (2015)

Prokineticin 2/PROK2 and Male Infertility
por: Petrella, Carla, et al.
Publicado: (2022)

PROK2/PROKR2 Signaling and Kallmann Syndrome
por: Dodé, Catherine, et al.
Publicado: (2013)

Prokineticin 2 (PROK2) is an important factor for angiogenesis in colorectal cancer
por: Kurebayashi, Hidetaka, et al.
Publicado: (2015)

ProkSeq for complete analysis of RNA-Seq data from prokaryotes
por: Mahmud, A K M Firoj, et al.
Publicado: (2020)

Large-scale quality assessment of prokaryotic genomes with metashot/prok-quality
por: Albanese, Davide, et al.
Publicado: (2021)

Variations in PROKR2, But Not PROK2, Are Associated With Hypopituitarism and Septo-optic Dysplasia
por: McCabe, Mark J., et al.
Publicado: (2013)

The Multiple Roles of EG-VEGF/PROK1 in Normal and Pathological Placental Angiogenesis
por: Alfaidy, Nadia, et al.
Publicado: (2014)

CTGF expression is up-regulated by PROK1 in early pregnancy and influences HTR-8/Svneo cell adhesion and network formation
por: Waddell, Jennifer M., et al.
Publicado: (2011)

The anti-tumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer
por: Goi, Takanori, et al.
Publicado: (2015)

ProkEvo: an automated, reproducible, and scalable framework for high-throughput bacterial population genomics analyses
por: Pavlovikj, Natasha, et al.
Publicado: (2021)

Silencing PROK2 Inhibits Invasion of Human Cervical Cancer Cells by Targeting MMP15 Expression
por: Wu, Min-Hua, et al.
Publicado: (2020)

Involvement of the Chemokine Prokineticin-2 (PROK2) in Alzheimer’s Disease: From Animal Models to the Human Pathology
por: Lattanzi, Roberta, et al.
Publicado: (2019)

Common polymorphic OTC variants can act as genetic modifiers of enzymatic activity
por: Lopes‐Marques, Mónica, et al.
Publicado: (2021)

Alzheimer's disease-associated inflammatory pathways might contribute to osteoporosis through the interaction between PROK2 and CSF3
por: Zhang, Wenzheng, et al.
Publicado: (2022)

FRI272 Sex-Specific Role Of ProkR2 Neurons Of The Posterior Amygdala In The Integration Of Odors And Neuroendocrine Responses
por: Cisneros-Larios, Brenda, et al.
Publicado: (2023)

Identification of PROK2 gene polymorphisms as predictors of methamphetamine use disorder risk and indicators of craving scale in the Chinese Han population
por: Jiang, Zhao, et al.
Publicado: (2023)

Narrowing down the role of common variants in the genetic predisposition to obesity
por: Calton, Melissa A, et al.
Publicado: (2009)

Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway
por: Cook, Ian H., et al.
Publicado: (2010)

A PK2/Bv8/PROK2 Antagonist Suppresses Tumorigenic Processes by Inhibiting Angiogenesis in Glioma and Blocking Myeloid Cell Infiltration in Pancreatic Cancer
por: Curtis, Valerie F., et al.
Publicado: (2013)

PI3K/AKT/mTOR pathway and its related molecules participate in PROK1 silence-induced anti-tumor effects on pancreatic cancer
por: Wang, Feng, et al.
Publicado: (2023)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes
por: Cuylen, Sara, et al.
Publicado: (2016)

Expression of GAD67 and Novel GAD67 Splice Variants During Human Fetal Pancreas Development: GAD67 Expression in the Fetal Pancreas
por: Korpershoek, Esther, et al.
Publicado: (2007)

Fetuin-A Inhibits Placental Cell Growth and Ciliogenesis in Gestational Diabetes Mellitus
por: Wang, Chia-Yih, et al.
Publicado: (2019)

Gene variants of adhesion molecules act as modifiers of disease severity in MS
por: Dardiotis, Efthimios, et al.
Publicado: (2017)

Common genetic variants, acting additively, are a major source of risk for autism
por: Klei, Lambertus, et al.
Publicado: (2012)

Lycopene Attenuates Hypoxia-Induced Testicular Injury by Inhibiting PROK2 Expression and Activating PI3K/AKT/mTOR Pathway in a Varicocele Adult Rat
por: Wang, Hongqiang, et al.
Publicado: (2021)

Missense variants in TMEM67 in a patient with Joubert syndrome
por: Huynh, Julie M., et al.
Publicado: (2018)

Modifier Role of Common RET Variants in Sporadic Medullary Thyroid Carcinoma
por: Skalniak, Anna, et al.
Publicado: (2021)

Trans-acting genetic variants causing multilocus imprinting disturbance (MLID): common mechanisms and consequences
por: Eggermann, Thomas, et al.
Publicado: (2022)

A Common Genetic Variant at 15q25 Modifies the Associations of Maternal Smoking during Pregnancy with Fetal Growth: The Generation R Study
por: Leermakers, Elisabeth T. M., et al.
Publicado: (2012)

Magnetic moment of $^{67}$Ni and $^{67}$Ni $\rightarrow ^{67}$Cu $\beta$-decay
por: Ríkovská, J, et al.
Publicado: (1996)

A novel modified RANKL variant can prevent osteoporosis by acting as a vaccine and an inhibitor
por: Ko, Young Jong, et al.
Publicado: (2021)

Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy
por: Lin, Rong, et al.
Publicado: (2017)

Common variants of fetal and maternal complement genes in preeclampsia: pregnancy specific complotype
por: Banadakoppa, Manu, et al.
Publicado: (2020)

“If I know I am on the pill and I get pregnant, it’s an act of God”: women’s views on fatalism, agency and pregnancy
por: Jones, Rachel K., et al.
Publicado: (2016)

Up-and-down immunity of pregnancy in humans
por: Le Bouteiller, Philippe, et al.
Publicado: (2017)

Identification of a common polymorphism in COQ8B acting as a modifier of thoracic aortic aneurysm severity
por: Landis, Benjamin J., et al.
Publicado: (2021)

Common variants in glyoxalase I do not increase chronic pancreatitis risk
por: Kaune, Tom, et al.
Publicado: (2019)

Risk of adverse cardiovascular events with use of inhaled long-acting bronchodilators in management of chronic obstructive pulmonary disease
por: Wang, Meng-Ting, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hl6n3l9judd5039rsuupo9a7ud