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The Metabolic Fate of ortho-Quinones Derived from Catecholamine Metabolites

ortho-Quinones are produced in vivo through the oxidation of catecholic substrates by enzymes such as tyrosinase or by transition metal ions. Neuromelanin, a dark pigment present in the substantia nigra and locus coeruleus of the brain, is produced from dopamine (DA) and norepinephrine (NE) via an i...

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Detalles Bibliográficos
Autores principales: Ito, Shosuke, Yamanaka, Yuta, Ojika, Makoto, Wakamatsu, Kazumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783898/
https://www.ncbi.nlm.nih.gov/pubmed/26828480
http://dx.doi.org/10.3390/ijms17020164