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The Metabolic Fate of ortho-Quinones Derived from Catecholamine Metabolites
ortho-Quinones are produced in vivo through the oxidation of catecholic substrates by enzymes such as tyrosinase or by transition metal ions. Neuromelanin, a dark pigment present in the substantia nigra and locus coeruleus of the brain, is produced from dopamine (DA) and norepinephrine (NE) via an i...
Autores principales: | Ito, Shosuke, Yamanaka, Yuta, Ojika, Makoto, Wakamatsu, Kazumasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783898/ https://www.ncbi.nlm.nih.gov/pubmed/26828480 http://dx.doi.org/10.3390/ijms17020164 |
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