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Icaritin Inhibits Collagen Degradation-Related Factors and Facilitates Collagen Accumulation in Atherosclerotic Lesions: A Potential Action for Plaque Stabilization

Most acute coronary syndromes result from rupture of vulnerable atherosclerotic plaques. The collagen content of plaques may critically affect plaque stability. This study tested whether Icaritin (ICT), an intestinal metabolite of Epimedium-derived flavonoids, could alter the collagen synthesis/degr...

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Detalles Bibliográficos
Autores principales: Zhang, Zong-Kang, Li, Jie, Yan, De-Xin, Leung, Wing-Nang, Zhang, Bao-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783903/
https://www.ncbi.nlm.nih.gov/pubmed/26828485
http://dx.doi.org/10.3390/ijms17020169