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Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

The hydrophilic nature of peptides and proteins renders them impermeable to cell membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics across the plasma membrane or epithelial and endothelial barriers, a permeation enhancing strategy must be employed. Cell-penetrat...

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Detalles Bibliográficos
Autores principales: Kristensen, Mie, Birch, Ditlev, Mørck Nielsen, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783919/
https://www.ncbi.nlm.nih.gov/pubmed/26840305
http://dx.doi.org/10.3390/ijms17020185