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Biological and Chemical Removal of Primary Cilia Affects Mechanical Activation of Chondrogenesis Markers in Chondroprogenitors and Hypertrophic Chondrocytes

Chondroprogenitors and hypertrophic chondrocytes, which are the first and last stages of the chondrocyte differentiation process, respectively, are sensitive to mechanical signals. We hypothesize that the mechanical sensitivity of these cells depends on the cell surface primary cilia. To test this h...

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Detalles Bibliográficos
Autores principales: Deren, Matthew E., Yang, Xu, Guan, Yingjie, Chen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783922/
https://www.ncbi.nlm.nih.gov/pubmed/26861287
http://dx.doi.org/10.3390/ijms17020188