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Generation of Potent Anti-Vascular Endothelial Growth Factor Neutralizing Antibodies from Mouse Phage Display Library for Cancer Therapy

Vascular endothelial growth factor (VEGF) is an important stimulator for angiogenesis in solid tumors. Blocking VEGF activity is an effective therapeutic strategy to inhibit tumor growth and metastasis. Avastin, a humanized monoclonal antibody recognizes VEGF, has been approved by the US Food and Dr...

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Detalles Bibliográficos
Autores principales: Lai, Yan-Da, Wu, Yen-Yu, Tsai, Yi-Jiue, Tsai, Yi-San, Lin, Yu-Ying, Lai, Szu-Liang, Huang, Chao-Yang, Lok, Ying-Yung, Hu, Chih-Yung, Lai, Jiann-Shiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783946/
https://www.ncbi.nlm.nih.gov/pubmed/26861297
http://dx.doi.org/10.3390/ijms17020214