Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease

Tumor necrosis factor (TNF) α is a major proinflammatory cytokine involved in the immune response in inflammatory bowel disease (IBD). Anti-TNF drugs such as infliximab and adalimumab are used to treat IBD; however, approximately 30% of patients do not respond to treatment. Individual genetic differ...

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Detalles Bibliográficos
Autores principales: Prieto-Pérez, Rocío, Almoguera, Berta, Cabaleiro, Teresa, Hakonarson, Hakon, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783957/
https://www.ncbi.nlm.nih.gov/pubmed/26861312
http://dx.doi.org/10.3390/ijms17020225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783957/
https://www.ncbi.nlm.nih.gov/pubmed/26861312
http://dx.doi.org/10.3390/ijms17020225

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