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Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease
Tumor necrosis factor (TNF) α is a major proinflammatory cytokine involved in the immune response in inflammatory bowel disease (IBD). Anti-TNF drugs such as infliximab and adalimumab are used to treat IBD; however, approximately 30% of patients do not respond to treatment. Individual genetic differ...
Autores principales: | Prieto-Pérez, Rocío, Almoguera, Berta, Cabaleiro, Teresa, Hakonarson, Hakon, Abad-Santos, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783957/ https://www.ncbi.nlm.nih.gov/pubmed/26861312 http://dx.doi.org/10.3390/ijms17020225 |
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