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Can follicular helper T cells be targeted to improve vaccine efficacy?

The success of most vaccines relies on the generation of antibodies to provide protection against subsequent infection; this in turn depends on a robust germinal centre (GC) response that culminates in the production of long-lived antibody-secreting plasma cells. The size and quality of the GC respo...

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Detalles Bibliográficos
Autores principales: Linterman, Michelle A., Hill, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784016/
https://www.ncbi.nlm.nih.gov/pubmed/26989476
http://dx.doi.org/10.12688/f1000research.7388.1