Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications

Low maternal circulating concentrations of placental growth factor (PlGF) are one of the hallmarks of human pregnancy complications, including fetal growth restriction (FGR) and early‐onset pre‐eclampsia (PE). Currently, PlGF is used clinically with other biomarkers to screen for high‐risk cases, al...

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Detalles Bibliográficos
Autores principales: Mizuuchi, Masahito, Cindrova‐Davies, Tereza, Olovsson, Matts, Charnock‐Jones, D Stephen, Burton, Graham J, Yung, Hong Wa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784173/
https://www.ncbi.nlm.nih.gov/pubmed/26648175
http://dx.doi.org/10.1002/path.4678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784173/
https://www.ncbi.nlm.nih.gov/pubmed/26648175
http://dx.doi.org/10.1002/path.4678

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