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Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications
Low maternal circulating concentrations of placental growth factor (PlGF) are one of the hallmarks of human pregnancy complications, including fetal growth restriction (FGR) and early‐onset pre‐eclampsia (PE). Currently, PlGF is used clinically with other biomarkers to screen for high‐risk cases, al...
Autores principales: | Mizuuchi, Masahito, Cindrova‐Davies, Tereza, Olovsson, Matts, Charnock‐Jones, D Stephen, Burton, Graham J, Yung, Hong Wa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784173/ https://www.ncbi.nlm.nih.gov/pubmed/26648175 http://dx.doi.org/10.1002/path.4678 |
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