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Rates of transition between amyloid and neurodegeneration biomarker states and to dementia among non-demented individuals: a population-based cohort study

BACKGROUND: We previously observed in a cross-sectional analysis that frequencies of amyloid and neurodegeneration biomarker states varied greatly by age among cognitively non-impaired participants, suggesting dynamic within-person processes. Our objective in this longitudinal study was to estimate...

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Detalles Bibliográficos
Autores principales: Jack, Clifford R., Therneau, Terry M., Wiste, Heather J., Weigand, Stephen D., Knopman, David S., Lowe, Val J., Mielke, Michelle M., Vemuri, Prashanthi, Roberts, Rosebud O., Machulda, Mary M., Senjem, Matthew L., Gunter, Jeffrey L., Rocca, Walter A., Petersen, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784263/
https://www.ncbi.nlm.nih.gov/pubmed/26597325
http://dx.doi.org/10.1016/S1474-4422(15)00323-3