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Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study

BACKGROUND: The host response to infection by Plasmodium falciparum, the parasite most often responsible for severe malaria, ranges from asymptomatic parasitaemia to death. The clinical trajectory of malaria is influenced by host genetics and parasite load, but the factors determining why some infec...

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Detalles Bibliográficos
Autores principales: Sobota, Rafal S., Dara, Antoine, Manning, Jessica E., Niangaly, Amadou, Bailey, Jason A., Kone, Abdoulaye K., Thera, Mahamadou A., Djimdé, Abdoulaye A., Vernet, Guy, Leissner, Philippe, Williams, Scott M., Plowe, Christopher V., Doumbo, Ogobara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784286/
https://www.ncbi.nlm.nih.gov/pubmed/26961973
http://dx.doi.org/10.1186/s12936-016-1189-6