Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations

BACKGROUND: Sort-seq is an effective approach for simultaneous activity measurements in a large-scale library, combining flow cytometry, deep sequencing, and statistical inference. Such assays enable the characterization of functional landscapes at unprecedented scale for a wide-reaching array of bi...

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Detalles Bibliográficos
Autores principales: Peterman, Neil, Levine, Erel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784318/
https://www.ncbi.nlm.nih.gov/pubmed/26956374
http://dx.doi.org/10.1186/s12864-016-2533-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784318/
https://www.ncbi.nlm.nih.gov/pubmed/26956374
http://dx.doi.org/10.1186/s12864-016-2533-5

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