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Hepatocellular adenoma classification: a comparative evaluation of immunohistochemistry and targeted mutational analysis

BACKGROUND: Four subtypes of hepatocellular adenomas (HCA) are recognized: hepatocyte-nuclear-factor-1α mutated (H-HCA), β-catenin-mutated type with upregulation of glutamine synthetase (b-HCA), inflammatory type (IHCA) with serum-amyloid-A overexpression, and unclassified type. Subtyping may be use...

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Detalles Bibliográficos
Autores principales: Margolskee, Elizabeth, Bao, Fei, de Gonzalez, Anne Koehne, Moreira, Roger K., Lagana, Stephen, Sireci, Anthony N., Sepulveda, Antonia R., Remotti, Helen, Lefkowitch, Jay H., Salomao, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784347/
https://www.ncbi.nlm.nih.gov/pubmed/26961851
http://dx.doi.org/10.1186/s13000-016-0475-5