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Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3

BACKGROUND: Assessment of DNA promoter methylation markers in cervical scrapings for the detection of cervical intraepithelial neoplasia (CIN) and cervical cancer is feasible, but finding methylation markers with both high sensitivity as well as high specificity remains a challenge. In this study, w...

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Detalles Bibliográficos
Autores principales: Boers, A., Wang, R., van Leeuwen, R. W., Klip, H. G., de Bock, G. H., Hollema, H., van Criekinge, W., de Meyer, T., Denil, S., van der Zee, A. G J., Schuuring, E., Wisman, G. B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784352/
https://www.ncbi.nlm.nih.gov/pubmed/26962367
http://dx.doi.org/10.1186/s13148-016-0196-3