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Phasing and structure of bestrophin-1: a case study in the use of heavy-atom cluster compounds with multi-subunit transmembrane proteins
The purification and three-dimensional crystallization of membrane proteins are commonly affected by a cumulation of pathologies that are less prevalent in their soluble counterparts. This may include severe anisotropy, poor spot shape, poor to moderate-resolution diffraction, crystal twinning, tran...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784663/ https://www.ncbi.nlm.nih.gov/pubmed/26960119 http://dx.doi.org/10.1107/S2059798315022524 |