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Disrupted balance of T cells under natalizumab treatment in multiple sclerosis

OBJECTIVE: To compare effects of natalizumab on inflammatory and regulatory T cells with regard to expression of α4-integrin (CD49d). METHODS: Twenty-seven natalizumab-naive and 8 natalizumab-treated patients with multiple sclerosis (MS), 7 patients with neuromyelitis optica (NMO) or NMO spectrum di...

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Detalles Bibliográficos
Autores principales: Kimura, Kimitoshi, Nakamura, Masakazu, Sato, Wakiro, Okamoto, Tomoko, Araki, Manabu, Lin, Youwei, Murata, Miho, Takahashi, Ryosuke, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784802/
https://www.ncbi.nlm.nih.gov/pubmed/27006971
http://dx.doi.org/10.1212/NXI.0000000000000210