Activity Based High-Throughput Screening for Novel O-GlcNAc Transferase Substrates Using a Dynamic Peptide Microarray

O-GlcNAcylation is a reversible and dynamic protein post-translational modification in mammalian cells. The O-GlcNAc cycle is catalyzed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). O-GlcNAcylation plays important role in many vital cellular events including transcription, cell cycle regulati...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Sharif, Suhela, Ruijtenbeek, Rob, Pieters, Roland J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784888/
https://www.ncbi.nlm.nih.gov/pubmed/26960196
http://dx.doi.org/10.1371/journal.pone.0151085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784888/
https://www.ncbi.nlm.nih.gov/pubmed/26960196
http://dx.doi.org/10.1371/journal.pone.0151085

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