Pathway-Based Genomics Prediction using Generalized Elastic Net

We present a novel regularization scheme called The Generalized Elastic Net (GELnet) that incorporates gene pathway information into feature selection. The proposed formulation is applicable to a wide variety of problems in which the interpretation of predictive features using known molecular intera...

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Detalles Bibliográficos
Autores principales: Sokolov, Artem, Carlin, Daniel E., Paull, Evan O., Baertsch, Robert, Stuart, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784899/
https://www.ncbi.nlm.nih.gov/pubmed/26960204
http://dx.doi.org/10.1371/journal.pcbi.1004790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784899/
https://www.ncbi.nlm.nih.gov/pubmed/26960204
http://dx.doi.org/10.1371/journal.pcbi.1004790

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