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Pathway-Based Genomics Prediction using Generalized Elastic Net
We present a novel regularization scheme called The Generalized Elastic Net (GELnet) that incorporates gene pathway information into feature selection. The proposed formulation is applicable to a wide variety of problems in which the interpretation of predictive features using known molecular intera...
Autores principales: | Sokolov, Artem, Carlin, Daniel E., Paull, Evan O., Baertsch, Robert, Stuart, Joshua M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784899/ https://www.ncbi.nlm.nih.gov/pubmed/26960204 http://dx.doi.org/10.1371/journal.pcbi.1004790 |
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