The Vascular Endothelial Growth Factor Inhibitors Ranibizumab and Aflibercept Markedly Increase Expression of Atherosclerosis-Associated Inflammatory Mediators on Vascular Endothelial Cells

INTRODUCTION: Recent studies have suggested that the VEGF inhibitors, Ranibizumab and Aflibercept may be associated with an excess of cardiovascular events, potentially driven by increasing atheroma instability, leading to plaque rupture and clinical events. Inflammation plays a key role in the prog...

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Detalles Bibliográficos
Autores principales: Arnott, Clare, Punnia-Moorthy, Gaya, Tan, Joanne, Sadeghipour, Sara, Bursill, Christina, Patel, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784900/
https://www.ncbi.nlm.nih.gov/pubmed/26959822
http://dx.doi.org/10.1371/journal.pone.0150688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784900/
https://www.ncbi.nlm.nih.gov/pubmed/26959822
http://dx.doi.org/10.1371/journal.pone.0150688

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