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Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event

Signal transducer and activator of transcription 5b (STAT5b) is a growth hormone (GH)-activated transcription factor and a master regulator of sexually dimorphic gene expression in the liver. Disruption of the GH hypothalamo-pituitary-liver axis controlling STAT5b activation can lead to metabolic dy...

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Detalles Bibliográficos
Autores principales: Oshida, Keiyu, Vasani, Naresh, Waxman, David J., Corton, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784905/
https://www.ncbi.nlm.nih.gov/pubmed/26959975
http://dx.doi.org/10.1371/journal.pone.0148308