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Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals

Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (W...

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Detalles Bibliográficos
Autores principales: Losick, Vicki P., Jun, Albert S., Spradling, Allan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784922/
https://www.ncbi.nlm.nih.gov/pubmed/26958853
http://dx.doi.org/10.1371/journal.pone.0151251