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Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells

INTRODUCTION: The antidiabetic drug metformin, currently undergoing trials for cancer treatment, modulates lipid and glucose metabolism both crucial in phospholipid synthesis. Here the effect of treatment of breast tumour cells with metformin on phosphatidylcholine (PtdCho) metabolism which plays a...

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Detalles Bibliográficos
Autores principales: Smith, Tim A. D., Phyu, Su M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784930/
https://www.ncbi.nlm.nih.gov/pubmed/26959405
http://dx.doi.org/10.1371/journal.pone.0151179