Cargando…
Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells
INTRODUCTION: The antidiabetic drug metformin, currently undergoing trials for cancer treatment, modulates lipid and glucose metabolism both crucial in phospholipid synthesis. Here the effect of treatment of breast tumour cells with metformin on phosphatidylcholine (PtdCho) metabolism which plays a...
Autores principales: | Smith, Tim A. D., Phyu, Su M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784930/ https://www.ncbi.nlm.nih.gov/pubmed/26959405 http://dx.doi.org/10.1371/journal.pone.0151179 |
Ejemplares similares
-
Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism
por: Smith, Tim A. D., et al.
Publicado: (2017) -
Extensive Decoupling of Metabolic Genes in Cancer
por: Reznik, Ed, et al.
Publicado: (2015) -
CDP-choline accumulation in breast and colorectal cancer cells treated with a GSK-3-targeting inhibitor
por: Phyu, Su Myat, et al.
Publicado: (2018) -
Targeting Phospholipid Metabolism in Cancer
por: Cheng, Menglin, et al.
Publicado: (2016) -
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
por: Gaglio, Daniela, et al.
Publicado: (2011)