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Serum Removal from Culture Induces Growth Arrest, Ploidy Alteration, Decrease in Infectivity and Differential Expression of Crucial Genes in Leishmania infantum Promastigotes

Leishmania infantum is one of the species responsible for visceral leishmaniasis. This species is distributed basically in the Mediterranean basin. A recent outbreak in humans has been reported in Spain. Axenic cultures are performed for most procedures with Leishmania spp. promastigotes. This model...

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Detalles Bibliográficos
Autores principales: Alcolea, Pedro J., Alonso, Ana, Moreno-Izquierdo, Miguel A., Degayón, María A., Moreno, Inmaculada, Larraga, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784933/
https://www.ncbi.nlm.nih.gov/pubmed/26959417
http://dx.doi.org/10.1371/journal.pone.0150172