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Serum Removal from Culture Induces Growth Arrest, Ploidy Alteration, Decrease in Infectivity and Differential Expression of Crucial Genes in Leishmania infantum Promastigotes
Leishmania infantum is one of the species responsible for visceral leishmaniasis. This species is distributed basically in the Mediterranean basin. A recent outbreak in humans has been reported in Spain. Axenic cultures are performed for most procedures with Leishmania spp. promastigotes. This model...
Autores principales: | Alcolea, Pedro J., Alonso, Ana, Moreno-Izquierdo, Miguel A., Degayón, María A., Moreno, Inmaculada, Larraga, Vicente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784933/ https://www.ncbi.nlm.nih.gov/pubmed/26959417 http://dx.doi.org/10.1371/journal.pone.0150172 |
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