Hsp72 (HSPA1A) Prevents Human Islet Amyloid Polypeptide Aggregation and Toxicity: A New Approach for Type 2 Diabetes Treatment

Type 2 diabetes is a growing public health concern and accounts for approximately 90% of all the cases of diabetes. Besides insulin resistance, type 2 diabetes is characterized by a deficit in β-cell mass as a result of misfolded human islet amyloid polypeptide (h-IAPP) which forms toxic aggregates...

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Detalles Bibliográficos
Autores principales: Rosas, Paola C., Nagaraja, Ganachari M., Kaur, Punit, Panossian, Alexander, Wickman, Georg, Garcia, L. Rene, Al-Khamis, Fahd A., Asea, Alexzander A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784952/
https://www.ncbi.nlm.nih.gov/pubmed/26960140
http://dx.doi.org/10.1371/journal.pone.0149409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784952/
https://www.ncbi.nlm.nih.gov/pubmed/26960140
http://dx.doi.org/10.1371/journal.pone.0149409

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