Cargando…

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

Around 7–17% of metastatic breast cancer patients will develop brain metastases, associated with a poor prognosis. To reach the brain parenchyma, cancer cells need to cross the highly restrictive endothelium of the Blood-Brain Barrier (BBB). As treatments for brain metastases are mostly inefficient,...

Descripción completa

Detalles Bibliográficos
Autores principales: Drolez, Aurore, Vandenhaute, Elodie, Julien, Sylvain, Gosselet, Fabien, Burchell, Joy, Cecchelli, Roméo, Delannoy, Philippe, Dehouck, Marie-Pierre, Mysiorek, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784983/
https://www.ncbi.nlm.nih.gov/pubmed/26958843
http://dx.doi.org/10.1371/journal.pone.0151155