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Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation

Invariant natural killer T (iNKT) cells produce cytokines interleukin-4 (IL-4) and IL-13 during type-2 inflammatory responses. However, the nature in which iNKT cells acquire type-2 cytokine competency and the precise contribution of iNKT cell–derived IL-4 and IL-13 in vivo remains unclear. Using IL...

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Detalles Bibliográficos
Autores principales: O'Brien, T F, Bao, K, Dell'Aringa, M, Ang, W X G, Abraham, S, Reinhardt, R L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785102/
https://www.ncbi.nlm.nih.gov/pubmed/26349658
http://dx.doi.org/10.1038/mi.2015.78