Cargando…

Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization

ABSTRACT: Bioorthogonal ligations have emerged as highly versatile chemical tools for biomedical research. The exceptionally fast reaction between 1,2,4,5-tetrazines and trans-cyclooctenes (TCOs), also known as tetrazine ligation, is frequently used in this regard. Growing numbers of applications fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Svatunek, Dennis, Denk, Christoph, Rosecker, Veronika, Sohr, Barbara, Hametner, Christian, Allmaier, Günter, Fröhlich, Johannes, Mikula, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785212/
https://www.ncbi.nlm.nih.gov/pubmed/27069284
http://dx.doi.org/10.1007/s00706-016-1668-z