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BK channel inactivation gates daytime excitability in the circadian clock

Inactivation is an intrinsic property of several voltage-dependent ion channels, closing the conduction pathway during membrane depolarization and dynamically regulating neuronal activity. BK K(+) channels undergo N-type inactivation via their β2 subunit, but the physiological significance is not cl...

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Detalles Bibliográficos
Autores principales: Whitt, Joshua P., Montgomery, Jenna R., Meredith, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785228/
https://www.ncbi.nlm.nih.gov/pubmed/26940770
http://dx.doi.org/10.1038/ncomms10837