TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions

Repressor/activator protein 1 (RAP1) is a highly conserved telomere-interacting protein. Yeast Rap1 protects telomeres from non-homologous end joining (NHEJ), plays important roles in telomere length control and is involved in transcriptional gene regulation. However, a role for mammalian RAP1 in te...

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Detalles Bibliográficos
Autores principales: Rai, Rekha, Chen, Yong, Lei, Ming, Chang, Sandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785230/
https://www.ncbi.nlm.nih.gov/pubmed/26941064
http://dx.doi.org/10.1038/ncomms10881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785230/
https://www.ncbi.nlm.nih.gov/pubmed/26941064
http://dx.doi.org/10.1038/ncomms10881

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