In Silico Screening, Alanine Mutation, and DFT Approaches for Identification of NS2B/NS3 Protease Inhibitors

To identify the ligand that binds to a target protein with high affinity is a nontrivial task in computer-assisted approaches. Antiviral drugs have been identified for NS2B/NS3 protease enzyme on the mechanism to cleave the viral protein using the computational tools. The consequence of the molecula...

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Detalles Bibliográficos
Autores principales: Balajee, R., Srinivasadesikan, V., Sakthivadivel, M., Gunasekaran, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785246/
https://www.ncbi.nlm.nih.gov/pubmed/27057355
http://dx.doi.org/10.1155/2016/7264080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785246/
https://www.ncbi.nlm.nih.gov/pubmed/27057355
http://dx.doi.org/10.1155/2016/7264080

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