Intracellular acidification is required for full activation of the sweet taste receptor by miraculin

Acidification of the glycoprotein, miraculin (MCL), induces sweet taste in humans, but not in mice. The sweet taste induced by MCL is more intense when acidification occurs with weak acids as opposed to strong acids. MCL interacts with the human sweet receptor subunit hTAS1R2, but the mechanisms by...

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Detalles Bibliográficos
Autores principales: Sanematsu, Keisuke, Kitagawa, Masayuki, Yoshida, Ryusuke, Nirasawa, Satoru, Shigemura, Noriatsu, Ninomiya, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785348/
https://www.ncbi.nlm.nih.gov/pubmed/26960429
http://dx.doi.org/10.1038/srep22807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785348/
https://www.ncbi.nlm.nih.gov/pubmed/26960429
http://dx.doi.org/10.1038/srep22807

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