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Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms

Multiple myeloma is a plasma cell neoplasm with an extremely variable clinical course. Animal models are needed to better understand its pathophysiology and for preclinical testing of potential therapeutic agents. Hematopoietic cells expressing the hypermorphic Rad50(s) allele show hematopoietic fai...

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Detalles Bibliográficos
Autores principales: Asai, Takashi, Hatlen, Megan A., Lossos, Chen, Ndiaye-Lobry, Delphine, Deblasio, Anthony, Murata, Kazunori, Fleisher, Martin, Cortizas, Elena M., Verdun, Ramiro E., Petrini, John, Nimer, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785351/
https://www.ncbi.nlm.nih.gov/pubmed/26961797
http://dx.doi.org/10.1038/srep22760