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Intrinsic phenotypic stability of a bi-stable auto regulatory gene

Even under homogenous conditions clonal cells can assume different distinct states for generations to follow, also known as epigenetic inheritance. Such long periods of different phenotypic states can be formed due to the existence of more than one stable state in the molecule concentration, where t...

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Detalles Bibliográficos
Autores principales: Besya, Azim-Berdy, Grönlund, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785359/
https://www.ncbi.nlm.nih.gov/pubmed/26961811
http://dx.doi.org/10.1038/srep22951