A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia

We have studied drug-response associated (DRA) gene expressions by applying a systems biology framework to the Cancer Cell Line Encyclopedia data. More than 4,000 genes are inferred to be DRA for at least one drug, while the number of DRA genes for each drug varies dramatically from almost 0 to 1,22...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoming, Yang, Jiasheng, Zhang, Yi, Fang, Yun, Wang, Fayou, Wang, Jun, Zheng, Xiaoqi, Yang, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785360/
https://www.ncbi.nlm.nih.gov/pubmed/26960563
http://dx.doi.org/10.1038/srep22811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785360/
https://www.ncbi.nlm.nih.gov/pubmed/26960563
http://dx.doi.org/10.1038/srep22811

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