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A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia
We have studied drug-response associated (DRA) gene expressions by applying a systems biology framework to the Cancer Cell Line Encyclopedia data. More than 4,000 genes are inferred to be DRA for at least one drug, while the number of DRA genes for each drug varies dramatically from almost 0 to 1,22...
Autores principales: | Liu, Xiaoming, Yang, Jiasheng, Zhang, Yi, Fang, Yun, Wang, Fayou, Wang, Jun, Zheng, Xiaoqi, Yang, Jialiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785360/ https://www.ncbi.nlm.nih.gov/pubmed/26960563 http://dx.doi.org/10.1038/srep22811 |
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