DBS-platform for biomonitoring and toxicokinetics of toxicants: proof of concept using LC-MS/MS analysis of fipronil and its metabolites in blood

A simple, sensitive and high throughput LC-MS/MS method was developed and validated for quantification of fipronil, fipronil sulfone and fipronil desulfinyl in rat and human dried blood spots (DBS). DBS samples were prepared by spiking 10 μl blood on DMPK-C cards followed by drying at room temperatu...

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Detalles Bibliográficos
Autores principales: Raju, Kanumuri Siva Rama, Taneja, Isha, Rashid, Mamunur, Sonkar, Ashish Kumar, Wahajuddin, Muhammad, Singh, Sheelendra Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785372/
https://www.ncbi.nlm.nih.gov/pubmed/26960908
http://dx.doi.org/10.1038/srep22447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785372/
https://www.ncbi.nlm.nih.gov/pubmed/26960908
http://dx.doi.org/10.1038/srep22447

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