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Interferon Lambda 4 Genotype Is Associated With Jaundice and Elevated Aminotransferase Levels During Acute Hepatitis C Virus Infection: Findings From the InC3 Collaborative

Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acut...

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Detalles Bibliográficos
Autores principales: Page, Kimberly, Mirzazadeh, Ali, Rice, Thomas M., Grebely, Jason, Kim, Arthur Y., Cox, Andrea L., Morris, Meghan D., Hellard, Margaret, Bruneau, Julie, Shoukry, Naglaa H., Dore, Gregory J., Maher, Lisa, Lloyd, Andrew R., Lauer, Georg, Prins, Maria, McGovern, Barbara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785397/
https://www.ncbi.nlm.nih.gov/pubmed/26973850
http://dx.doi.org/10.1093/ofid/ofw024