Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel

Microglial activation is implicated in the pathogenesis of Parkinson’s disease (PD). Although the etiology of PD remains unclear, age and male gender are known PD risk factors. By comparing microglia and dopaminergic (DA) neurons in the substantia nigra (SN) of male and female mice of different ages...

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Detalles Bibliográficos
Autores principales: Wu, Shih-Ying, Chen, Yun-Wen, Tsai, Sheng-Feng, Wu, Sheng-Nan, Shih, Yao-Hsiang, Jiang-Shieh, Ya-Fen, Yang, Ting-Ting, Kuo, Yu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785403/
https://www.ncbi.nlm.nih.gov/pubmed/26960267
http://dx.doi.org/10.1038/srep22864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785403/
https://www.ncbi.nlm.nih.gov/pubmed/26960267
http://dx.doi.org/10.1038/srep22864

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