Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak

KEY POINTS: Ca leak from the sarcoplasmic reticulum through the ryanodine receptor (RyR) reduces the amplitude of the Ca transient and slows its rate of decay. In the presence of β‐adrenergic stimulation, RyR‐mediated Ca leak produces a biphasic decay of the Ca transient with a fast early phase and...

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Detalles Bibliográficos
Autores principales: Sankaranarayanan, Rajiv, Li, Yatong, Greensmith, David J., Eisner, David A., Venetucci, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785612/
https://www.ncbi.nlm.nih.gov/pubmed/26537441
http://dx.doi.org/10.1113/JP271473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785612/
https://www.ncbi.nlm.nih.gov/pubmed/26537441
http://dx.doi.org/10.1113/JP271473

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