Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials

BACKGROUND: Proarrhythmia assessment is one of the major concerns for regulatory bodies and pharmaceutical industry. ICH guidelines recommending preclinical tests have been established in attempt to eliminate the risk of drug-induced arrhythmias. However, in the clinic, arrhythmia occurrence is dete...

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Detalles Bibliográficos
Autores principales: Wiśniowska, Barbara, Tylutki, Zofia, Wyszogrodzka, Gabriela, Polak, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785617/
https://www.ncbi.nlm.nih.gov/pubmed/26960809
http://dx.doi.org/10.1186/s40360-016-0053-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785617/
https://www.ncbi.nlm.nih.gov/pubmed/26960809
http://dx.doi.org/10.1186/s40360-016-0053-1

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