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Rutin attenuates intestinal toxicity induced by Methotrexate linked with anti-oxidative and anti-inflammatory effects

BACKGROUND: Methotrexate (MTX) is recognized as an anti-metabolite in cancer chemotherapy and is associated with various toxicities assigned to inflammation and oxidative stress. Rutin has been reported to have significant anti-inflammatory, antioxidant along with antiulcer properties. The present s...

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Detalles Bibliográficos
Autores principales: Gautam, Raju, Singh, Manjari, Gautam, Swetlana, Rawat, Jitendra Kumar, Saraf, Shubhini A, Kaithwas, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785621/
https://www.ncbi.nlm.nih.gov/pubmed/26965456
http://dx.doi.org/10.1186/s12906-016-1069-1