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Endogenously-expressed NH(2)-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands

BACKGROUND: The circumsporozoite protein is the most abundant polypeptide expressed by sporozoites, the malaria parasite stage capable of infecting humans. Sporozoite invasion of mosquito salivary glands prior to transmission is likely mediated by a receptor/ligand-like interaction of the parasites...

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Detalles Bibliográficos
Autores principales: Kojin, Bianca B., Costa-da-Silva, André Luis, Maciel, Ceres, Henriques, Dayane Alves, Carvalho, Danilo O., Martin, Kelcie, Marinotti, Osvaldo, James, Anthony A., Bonaldo, Myrna C., Capurro, Margareth Lara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785649/
https://www.ncbi.nlm.nih.gov/pubmed/26964736
http://dx.doi.org/10.1186/s12936-016-1207-8